Plain-English translation of NCT05719779 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a mandibular advanced device—a custom-fitted dental appliance that gently moves your lower jaw forward to help keep your airway open during sleep. The study focuses on people who have been treated for oropharyngeal cancer with radiation therapy and are now experiencing snoring or breathing pauses during sleep. Researchers want to see if this device can reduce these sleep problems and improve how well you sleep.
Many people who have received radiation therapy for throat cancer develop snoring and sleep apnea (breathing stops during sleep), which can cause fatigue and poor sleep quality. Currently, there are limited treatment options specifically designed for cancer survivors with these problems, so this trial aims to see whether the jaw advancement device could be a helpful solution.
You likely qualify if…
You likely don't qualify if…
You would be fitted with a custom dental device that moves your lower jaw forward to help keep your airway open while you sleep. The study uses two versions of the device—one that actively advances your jaw and one in a neutral position—and you would wear each for a period of time so researchers can compare how well each works for you. You would likely have clinic visits for fitting, adjustment, and follow-up assessments to measure improvements in your snoring and sleep quality.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Canada
Sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Enrollment target
~35 participants
Started
February 2023
Primary completion
December 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in August 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Gilles Lavigne, DMD, PhD
Centre hospitalier de l'Université de Montréal (CHUM)
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.