Plain-English translation of NCT05723588 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing repetitive transcranial magnetic stimulation (rTMS)—a noninvasive brain stimulation technique—to help Veterans with PTSD quit smoking. Some participants will receive active treatment, while others will receive a sham (fake) version as a control. The research team will also use brain imaging to understand how the treatment works and tailor it to each person.
Veterans with PTSD struggle especially hard to quit smoking, and current treatments don't work well enough for this group. This study aims to see if brain stimulation can improve smoking cessation outcomes by targeting the brain circuits involved in tobacco addiction.
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You will be randomly assigned to receive either active or sham brain stimulation as part of a smoking cessation program. The treatment involves sessions where a magnetic coil is placed on your scalp to stimulate brain activity—it's painless but may feel like tapping on your head. You'll also have brain imaging scans to help personalize your treatment, and you'll work with the research team on your quit attempt.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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