Plain-English translation of NCT05724992 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
The PROPH-ITA Study is looking for genetic changes that might increase someone's risk of pancreatic cancer. If you have a family member with pancreatic cancer, researchers want to test your DNA using a saliva sample to see if you carry genes that could make you more susceptible to the disease. This information could help doctors monitor your health more closely and catch any problems early.
Pancreatic cancer can run in families, and some people inherit genetic mutations that increase their risk. By identifying who carries these mutations, doctors can provide better monitoring and potentially catch cancer earlier when treatment options may be more effective.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will provide a saliva sample by swabbing the inside of your cheek—a quick, painless process. The sample will then be tested for 41 different genes known to be related to pancreatic cancer risk. Your results will help researchers understand genetic patterns in families affected by pancreatic cancer and may guide your own healthcare decisions going forward.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
Italy
Sponsor
Associazione Italiana per lo Studio del Pancreas
Collaborators
General and Pancreatic Surgery Unit, University of Verona, Fondazione Valsecchi
Enrollment target
~3,000 participants
Started
December 2022
Primary completion
December 2027
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in February 2023.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Erica Secchettin, PharmD
Associazione Italiana per lo Studio del Pancreas
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.