Plain-English translation of NCT05730023 on ClinicalTrials.gov ↗ · Source last updated · Translation generated ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether a treatment called transcranial direct current stimulation (tDCS)—a non-invasive way to gently stimulate specific areas of the brain—can help people with primary progressive aphasia when combined with personalized language training. Participants will receive either active tDCS or placebo tDCS paired with customized speech therapy over two weeks. Researchers will measure changes in language ability and examine how the treatment affects the brain.
Primary progressive aphasia gradually takes away a person's ability to speak, understand, or use language. Current treatments are limited, so this trial is exploring whether this combination of brain stimulation and targeted language therapy might slow decline or improve communication abilities.
You likely qualify if…
You likely don't qualify if…
You would visit one of four Italian research centers for testing and treatment. First, you'll have baseline assessments including language tests, a neurological exam, and brain imaging (MRI or PET scan). Then, for two weeks, you'll attend five days a week for 25-minute sessions combining either active or placebo brain stimulation with personalized language training. Finally, you'll return for testing right after treatment ends and again three months later to see if your language abilities have improved.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Italy