Plain-English translation of NCT05732103 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing a new medication called to see if it can help people whose blood cancers (acute myeloid leukemia or myelodysplastic syndromes) have returned or stopped responding to previous treatments. Researchers will first test different doses of the medication to find the safest and most effective amount, then give that dose to more patients to confirm it works and monitor side effects.
People with these blood cancers often run out of effective treatment options when their disease comes back or becomes resistant to standard therapies. This trial exists to see if this medication might offer a new hope for patients in that difficult situation.
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You will visit the study site regularly to receive the medication by mouth, at a dose determined by earlier participants' responses. The study has two phases: first, researchers test increasing doses to find the right amount, then they give that dose to more patients to confirm safety and effectiveness. Throughout the trial, you'll have blood tests and check-ups to monitor how the medication is working and watch for side effects. The exact length and frequency of visits depend on which phase of the trial you join.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
United States