Recruiting

Testing a New Way to Diagnose Asthma in Children

Plain-English translation of NCT05734261 on ClinicalTrials.gov ↗ · Source last updated September 2023 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing whether a technique called forced oscillations can improve how doctors diagnose asthma in children. Right now, doctors use a test where children breathe into a machine after inhaling methacholine (a substance that briefly tightens airways in people with asthma), but this test requires a lot of cooperation from children and sometimes doesn't work well. The study wants to see if the forced oscillations technique—which is easier and requires less effort from the child—can predict the same results, making asthma diagnosis faster and more reliable.

Asthma is very common in children, affecting about 1 in 10 kids in France. The current breathing test used to diagnose asthma doesn't always work in children because it's hard for them to cooperate fully, which can lead to missed diagnoses. This trial exists to find a simpler, easier way to test children that gives reliable results.

Do you qualify?

You likely qualify if…

you are between 6 and 16 years old
you have been referred for asthma testing because your doctor suspects you might have asthma
your baseline lung function is at least 60%
you stopped taking inhaled corticosteroids at least 3 weeks before joining
you are willing to give oral consent, and at least one parent or legal guardian consents

You likely don't qualify if…

you have used a quick-relief inhaler in the past 6 hours
you have used certain long-acting asthma medications in the past 36 hours
you have had a respiratory infection (chest cold or similar) in the past 3 weeks
you have epilepsy that is being treated with medication

What participation looks like

You will visit the pulmonary (lung) function testing lab where doctors will ask you to breathe into a machine using two different techniques. First, they'll use the new forced oscillations technique, which is simple—you just breathe normally into a mouthpiece. Then you'll inhale gradually increasing doses of methacholine and repeat the breathing tests to see how your airways respond. The whole visit will take a few hours, and the goal is to compare how well the two techniques work for diagnosing asthma.

AI-generated summary from trial data · Jun 2, 2026 · Not medical advice

Trial locations(1 site)

France

CHU de Montpellier, Montpellier