Plain-English translation of NCT05736471 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Depression research guide →Researchers are trying to understand why people with depression sometimes struggle with flexible thinking — the ability to shift between different thoughts or approaches. This study uses online surveys and short thinking tasks to measure cognitive flexibility and see how it relates to mood and depression. The results will help researchers develop better tools to study and eventually treat depression.
Current methods for measuring how depression affects thinking aren't well understood or standardized. This study aims to figure out which tests are most reliable, valid, and useful so researchers can use them in future depression studies and treatments.
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You will complete one online session through a survey platform where you'll answer questions about your mood and thoughts, and complete short computer-based thinking tasks. The whole session takes place on your own computer at home, and you can do it at a time that's convenient for you. There are no follow-up visits — it's a single session only.
AI-generated summary from trial data · Jul 2, 2026 · Not medical advice
United States
University of Minnesota
Enrollment target
~2,500 participants
Started
February 2023
Primary completion
May 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Matthew Maple
University of Minnesota
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.