Plain-English translation of NCT05738603 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
During head and neck free flap transplant surgery, maintaining stable blood pressure is crucial for the success of the transplanted tissue. This trial is testing a new monitoring system called the Hypotension Prediction Index that aims to alert surgeons before dangerous blood pressure drops occur, so they can prevent them. The study will compare this new monitoring approach to standard care to see if it reduces complications and improves outcomes.
Low blood pressure during surgery can damage the transplanted tissue and lead to complications. Current monitoring methods only react after a problem happens, rather than predicting it before it occurs. This new treatment aims to catch problems earlier, giving doctors time to prevent serious drops in blood pressure.
You likely qualify if…
You likely don't qualify if…
If you enroll, you will be randomly assigned to either receive standard blood pressure monitoring or the new Hypotension Prediction Index monitoring system during your surgery. Both groups will receive excellent surgical care; the only difference is the monitoring method used. Your surgical team will use the monitoring information to manage your blood pressure throughout the operation, and your recovery will be tracked to see how well your transplanted tissue performs.
AI-generated summary from trial data · Jun 16, 2026 · Not medical advice
Poland
Sponsor
Jakub Szrama
Enrollment target
~206 participants
Started
September 2024
Primary completion
September 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in August 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jakub Szrama, Ph.D.
Poznan Univeristy of Medical Sciences, Department of Anesthesiology, Intensive Therapy
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.