Plain-English translation of NCT05741697 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial tests whether high-flow nasal cannula — a device that delivers warm, humidified oxygen at high flow rates through your nose — works as well as non-invasive ventilation (a mask-based breathing support) for patients hospitalized with a severe flare-up of bronchiectasis. Both treatments help your lungs work more easily without requiring a breathing tube placed in your windpipe.
Non-invasive ventilation is the standard treatment for severe breathing problems in bronchiectasis patients, but doctors want to know if this newer high-flow oxygen treatment might work just as well or better. There is limited research on how well the high-flow approach works in this specific situation.
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You will be admitted to the respiratory intensive care unit and randomly assigned to receive either high-flow nasal cannula or non-invasive ventilation through a mask. The research team will monitor how well each treatment works for your breathing and recovery. Your participation will continue during your hospital stay as your doctors assess which treatment is helping you breathe better.
AI-generated summary from trial data · Sep 4, 2026 · Not medical advice
Egypt
Collaborators
WGEKHALEEL, AARMHUSSIEN
Enrollment target
~20 participants
Started
March 2023
Primary completion
November 2026
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in September 2026.
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Central contact
ahmad shaddad, MD
Assiut University
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