Plain-English translation of NCT05741775 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Migraine research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This study is testing whether two different types of physical therapy — aerobic exercise training and biofeedback relaxation training — can help reduce migraine symptoms in university students. When you exercise or learn to relax tense muscles, your body naturally releases chemicals that act as painkillers and mood boosters, which may help prevent migraines or make them less severe.
Migraines are a chronic condition that affects many students and interferes with their daily lives. Research shows that regular exercise and muscle relaxation can help reduce how often migraines happen and how bad they are, but doctors want to test which approach works best for young adults.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to one of three groups. If assigned to the exercise group, you'll attend three 40-minute sessions per week for six weeks, doing walking, stationary cycling, and neck exercises with warm-up and cool-down time. If assigned to the relaxation group, you'll learn biofeedback training three times per week for 30 minutes, where sensors help you learn to relax tense neck and forehead muscles. If assigned to the control group, you'll receive educational materials about migraines now and can try one of the treatments later.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
Malaysia