Plain-English translation of NCT05741853 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether customized speech and language therapy—designed specifically for people who speak two languages—can help bilingual individuals with primary progressive aphasia, a condition that gradually makes speaking and understanding language more difficult. Researchers will compare how well the therapy works in each of a person's two languages and whether the amount someone uses each language affects how much they improve.
While speech therapy has been shown to help people who speak only one language with this condition, very little research exists on whether therapy works the same way—or needs to be different—for people who speak two languages. This study aims to fill that gap and better understand how bilingualism affects a person's ability to recover language skills.
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If you join the treatment group, you will receive customized speech therapy in both of your languages—either naming practice or script-based conversation training depending on your type of aphasia. You'll be tested before treatment starts, right after treatment ends, and again at 6 and 12 months after finishing. You may also have a brain scan before treatment begins. The study will also recruit some participants who only complete assessments and don't receive therapy, to help researchers understand what changes naturally over time.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
United States
Spain