Plain-English translation of NCT05742360 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study looks at whether using a breathing machine called CPAP can help lower blood pressure in people with moderate-to-severe obstructive sleep apnea who struggle with excessive daytime sleepiness. Researchers will follow newly diagnosed patients over 6 months to measure how the treatment affects their 24-hour blood pressure, regular blood pressure readings, and alertness. The goal is to understand whether treating sleep apnea with this device can also improve heart health.
Many people with sleep apnea have high blood pressure, which increases their risk of heart disease and stroke. Researchers want to know whether treating the sleep apnea with this breathing machine can help bring down blood pressure and improve overall health in patients who experience severe daytime sleepiness.
You would start using a CPAP breathing machine as prescribed by your doctor. At the beginning and again after 6 months, you would visit the research center for measurements including 24-hour ambulatory blood pressure monitoring (wearing a cuff that checks your pressure throughout the day and night), regular office blood pressure checks, and a simple reaction-time test. You would also complete some questionnaires about your health, lifestyle, and symptoms, and provide a blood sample to check your kidney function and blood pressure medication levels.
AI-generated summary from trial data · Aug 3, 2026 · Not medical advice
United States
Sponsor
Ohio State University
Collaborators
University of Pennsylvania
Enrollment target
~227 participants
Started
February 2023
Primary completion
March 2027
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in July 2026.