Plain-English translation of NCT05747976 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This is a research study that follows children and adolescents who developed severe weight gain before age 5. Researchers collect information about your child's health history, family background, body measurements, genetic information, and how they respond to different treatments. The goal is to understand why some children develop obesity and identify which ones might benefit from genetic testing.
Severe early-onset obesity in children can sometimes have a genetic cause that doctors should know about. By studying many children with this condition, researchers hope to learn which children should be tested for genetic disorders and how to better help them manage their weight.
You likely qualify if…
You likely don't qualify if…
Your child will be part of an observational study, meaning researchers will gather and track information rather than test a new medication. During visits, the team will collect basic information (age, family history), take body measurements, do blood work or other routine medical tests, and may ask you to complete questionnaires. Over time, they will also record how your child responds to treatments you may already be receiving, helping them build a better understanding of obesity in children.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Enrollment target
~500 participants
Started
August 2020
Primary completion
December 2030
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Stephanie Sisley, MD
Baylor College of Medicine
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.