Plain-English translation of NCT05751018 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a medication called in patients with advanced lung cancer that has a specific genetic change (HER2 amplification or mutation). is a targeted drug designed to attack cancer cells carrying these genetic changes. Researchers want to see if this medication is safe and how well it works as a first-line treatment for eligible patients.
Many patients with advanced lung cancer need better treatment options. This medication works differently than standard chemotherapy by targeting a specific genetic change in tumors. This trial aims to show whether this treatment can help patients with HER2-altered lung cancer live longer and have fewer side effects.
You likely qualify if…
You likely don't qualify if…
As a participant, you would take the medication by mouth daily. You would have regular visits to the hospital or clinic for blood tests, heart imaging, and scans to monitor how you're responding to treatment. The study involves about 18 patients total, and you would be monitored for safety and how well the medication is working against your cancer.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
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