Plain-English translation of NCT05755217 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers studied how dark chocolate affects the kidneys by measuring blood flow changes. Previous research suggested that dark chocolate (which is rich in cocoa and compounds called flavonoids) might improve how well kidneys receive oxygen. This trial examined whether dark chocolate could change kidney blood flow patterns using ultrasound imaging, comparing it to white chocolate as a control.
While earlier studies hinted that dark chocolate might benefit the heart and kidneys, scientists needed to understand exactly how it affects kidney blood flow and whether these effects are safe for people with kidney disease. This trial filled that gap by directly measuring kidney blood flow responses.
Participants received a single dose of dark chocolate (70% cocoa) or white chocolate by mouth, each weighing 1 gram per kilogram of their body weight. Before and after eating the chocolate, researchers used kidney ultrasound with Doppler technology to measure how blood flowed through the kidney arteries, tracking changes in blood vessel resistance. The trial examined whether dark chocolate caused any measurable shifts in kidney blood flow compared to white chocolate.
AI-generated summary from trial data · Jul 2, 2026 · Not medical advice
Switzerland
Sponsor
Gregoire Wuerzner; MD
Enrollment target
~33 participants
Started
February 2023
Primary completion
September 2025
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2026.