Plain-English translation of NCT05755672 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
The On-CALL study is collecting blood and tissue samples from patients with metastatic colorectal cancer (cancer that has spread to other organs) who are receiving treatment aimed at cure. Researchers want to understand how the cancer changes and evolves during treatment, and why some patients respond well while others don't. By studying these samples, they hope to find new ways to predict which treatments will work best for each person.
Even with modern treatments, some patients with metastatic colorectal cancer don't respond well or their cancer comes back. Scientists don't fully understand why this happens or how to predict it early. This study aims to identify biological markers in blood and tissue that could help doctors know sooner if a treatment is working, so they can make better treatment decisions.
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If you join this study, you will continue your cancer treatment as planned with your doctors. The study team will collect blood samples and tissue samples (from biopsies or surgery) before, during, and after your treatment to track how your cancer evolves. You may also have your medical records reviewed and be asked about your treatment outcomes over time. The study aims to enroll 100 patients and will follow their progress to understand which biological patterns predict treatment success.
AI-generated summary from trial data · Jul 15, 2026 · Not medical advice
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