Plain-English translation of NCT05760924 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a newer way to implant and program heart pacemakers (called left bundle branch pacing) in people whose hearts haven't responded well to standard pacemaker therapy. About 30-50% of heart failure patients don't improve with traditional dual-chamber pacemakers, and this study explores whether the new pacing technique might help them. Researchers will compare three approaches: keeping the standard pacemaker setup, switching to the newer pacing technique alone, or combining both techniques.
Many heart failure patients receive standard pacemakers but don't get better — their heart function doesn't improve and their symptoms stay the same. Doctors are looking for better options for these patients, and the newer pacing technique shows promise in early studies as a way to more effectively coordinate the heart's beating.
You likely qualify if…
You likely don't qualify if…
If you qualify, you'll be randomly assigned to one of three groups: continuing your standard pacemaker, having it replaced with a new pacing system that targets the heart's bundle branch, or having a combination approach. You'll have the pacemaker procedure at the research center in Russia and then return for follow-up visits to check how well the new system is working. The study will track your heart function, symptoms, and quality of life over time to see which approach works best.
AI-generated summary from trial data · Jul 10, 2026 · Not medical advice
Russia