Plain-English translation of NCT05761015 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether combining a walking rehabilitation program with short-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) can help people with painful hip or knee arthritis walk more easily and stay active. Researchers want to understand if the medication helps you exercise more effectively, and whether better footwear and supportive shoe inserts improve your walking comfort. The goal is to help you build a sustainable walking routine that reduces your pain and improves your quality of life.
Many people with hip and knee arthritis struggle to stay active because of pain, and they may not exercise regularly even though movement is beneficial. This trial explores whether pain relief medication can help you exercise without discomfort, allowing you to build better walking habits that last beyond the study.
You likely qualify if…
You likely don't qualify if…
You will visit the clinic five times over approximately 14 weeks. At your first visit, researchers will check that you qualify, explain the study, and have you see a foot specialist who may recommend better shoes or insoles. You'll take a short walk test before and 45 minutes after taking the study medication to see if it helps your walking. If it does, you'll enter a 12-week walking program split into two 6-week phases, where you'll walk regularly and keep a diary of your pain and activity. You'll have blood tests at the middle and end of the study to make sure the medication is safe for you, and you'll complete questionnaires about your pain, mood, and overall improvement.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
France