Plain-English translation of NCT05772013 on ClinicalTrials.gov ↗ · Source last updated · Translation generated ·
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing azithromycin, an antibiotic used to prevent flare-ups in people with chronic obstructive pulmonary disease (COPD). The study wants to find out whether people who have been taking this medication for at least 3 months should continue it year-round, stop it completely, or take it only during the winter months when flare-ups are more common.
Doctors aren't sure about the best way to use this medication long-term. No one knows if it stays effective after a year, what happens when people stop taking it, or whether taking it seasonally could work just as well while reducing unnecessary medication exposure.
You likely qualify if…
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You will be randomly assigned to one of three groups: taking the medication continuously throughout the trial, taking it only from October through March with placebo the rest of the year, or taking placebo continuously. The trial will last about 24 months, and you will be followed by your GP or specialist clinic to track how many flare-ups you experience and monitor your health. You will not need baseline heart tracings (ECGs) as part of the trial.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
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