Plain-English translation of NCT05776797 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial tests whether a specific heart rhythm procedure called atrioventricular junction ablation works better than medication alone for people who have atrial fibrillation (a condition where the heart beats irregularly) and already have a special heart device called a cardiac resynchronization therapy device. You would be randomly assigned to either receive the procedure or continue with optimized medications.
People with atrial fibrillation who have a special heart device sometimes still have problems with irregular heartbeats and may need emergency visits or hospitalizations. Researchers want to know if this procedure can help control the irregular heartbeat better than medication alone.
You likely qualify if…
You likely don't qualify if…
If you are selected, you will be randomly placed into one of two groups: either you will have the minimally invasive procedure done fairly soon after enrollment, or you will continue taking optimized medications. Either way, you will visit the clinic regularly for follow-up appointments to monitor your heart health. If you are in the medication group but your condition gets worse, your doctors may offer you the procedure at any time during the trial.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
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