Plain-English translation of NCT05782777 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After you receive a stent to open a blocked heart artery, doctors want to lower your cholesterol to prevent future problems. This trial is testing whether taking ezetimibe combined with a high-dose statin works better than taking a high-dose statin alone. Both approaches use proven, existing medications — the question is which combination works best for you.
Cholesterol buildup is a major reason heart stents can fail over time. Doctors want to find the most effective medication approach to keep your stent working and prevent future heart problems.
You likely qualify if…
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You will be randomly assigned to take either the combination of ezetimibe plus a high-dose statin, or a high-dose statin alone. You'll take your assigned medication daily for one year and attend follow-up visits to check how well your stent is working and how your cholesterol levels are doing. Some participants with longer blockages may also have a special imaging test called OCT to help doctors optimize your stent placement during the procedure.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
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