Receive a new type of stent and take a simplified blood thinner regimen

Back to ST Elevation Myocardial Infarction trials

What is this trial?

This trial is testing a new approach to treating sudden heart attacks (STEMI). Participants receive a special stent coated with sirolimus—a medication that helps prevent the artery from closing again—combined with either a simplified blood-thinning plan (one medication for 12 months) or the standard approach (two blood-thinning medications). The goal is to see if the new stent and simpler medication regimen can improve outcomes and reduce complications.

After a heart attack, the artery heals slowly and remains at risk for dangerous complications. Researchers believe newer stent technology combined with a simplified blood-thinning strategy might promote faster, safer healing and reduce the need for long-term dual medications.

Do you qualify?

You likely qualify if…

you are at least 18 years old
you have been diagnosed with an ST-elevation myocardial infarction (sudden heart attack) and received the trial stent during an emergency procedure
you are willing and able to understand and sign an informed consent form
you are able to take blood-thinning medications as prescribed for at least 6 months
the artery blockage was successfully treated with the study stent and is now at least 70% open

You likely don't qualify if…

you have a known allergy to aspirin, ticagrelor, prasugrel, or sirolimus
you are pregnant or planning to become pregnant
you are already on blood thinners due to a clotting disorder or recent stent from another procedure
you have a mechanical complication of your heart attack or a life expectancy of less than one year
you are unable or unwilling to follow the medication schedule or study procedures

What participation looks like

You will receive an emergency stent procedure during your heart attack treatment. After that, you will be randomly assigned to take either one blood-thinning medication for 12 months, or the standard two blood-thinning medications. You will need to take your medications exactly as prescribed and attend follow-up visits to monitor your heart health and check for any complications. The study will continue for 12 months after your procedure.

New stent coated with medicine plus simplified blood thinner strategy for heart attacks

What is this trial?

Do you qualify?

What participation looks like

Trial locations(2 sites)