Plain-English translation of NCT05786131 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
When you have a heart attack caused by multiple blocked arteries, doctors need to decide: should they open just the main artery that caused the attack, or open all the blocked arteries at once? This trial is testing whether opening all significantly blocked arteries leads to better outcomes than opening only the culprit artery and treating other blockages with medication alone.
Many heart attack patients have blockages in multiple arteries, but doctors aren't sure whether fixing all of them immediately is safer and more effective than fixing only the main one causing the attack. This trial aims to answer that important question.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to one of two groups. One group will receive opening of all significantly blocked arteries (either during the same procedure, later in the hospital stay, or within 45 days). The other group will receive opening of only the main blocked artery and medical treatment for any remaining blockages. Both groups will receive optimal heart medications and be followed for outcomes over time. The trial is enrolling about 3,390 patients at multiple centers.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
Austria
Germany