DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations — Stella
Phase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.
(27 sites) United Kingdom
Belfast City Hospital, Belfast University Hospital Birmingham, Birmingham Birmingham Children's Hospital, Birmingham Bristol Royal Hospital for Children, Bristol Bristol Haematology and Oncology Centre, Bristol Show all 27 locations Key details Phase
Safety & dosing / Large-scale testing
Sponsor
Cancer Research UK
Collaborators
University of Manchester, University of Birmingham
Enrollment target
~30 participants
Primary completion
October 2029
Age range
12 Years and older
Last updated December 2025