Plain-English translation of NCT05789433 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research study is testing whether aerobic exercise can help colorectal cancer survivors rebuild healthy muscle tissue after treatment. Researchers want to compare two groups: one doing aerobic exercise (about 225 minutes per week) and another doing gentle stretching. The goal is to see if exercise can improve muscle quality and reduce unwanted fat buildup in muscles.
Cancer treatment and recovery can cause loss of muscle strength and quality, which affects how people feel and function in daily life. This study aims to find out whether exercise is an effective way to help survivors rebuild their muscles and improve their overall health after cancer.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will be randomly assigned to either an aerobic exercise group or a stretching group. The aerobic exercise group will do about 225 minutes of moderate-to-vigorous exercise per week, while the stretching group will do gentle static stretching. You will likely have visits to measure your muscle health, and researchers may use imaging scans to look at your muscle quality over time.
AI-generated summary from trial data · Aug 11, 2026 · Not medical advice
United States
Sponsor
AdventHealth Translational Research Institute
Collaborators
National Cancer Institute (NCI)
Enrollment target
~70 participants
Started
May 2023
Primary completion
March 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Justin C. Brown, Ph.D.
AdventHealth
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.