Plain-English translation of NCT05790785 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Type 1 Diabetes research guide →This research study is following children who have been recently diagnosed with type 1 diabetes to learn how their blood vessels and heart health change during the first two years after diagnosis. Doctors know that type 1 diabetes can affect the heart and blood vessels over time, but they don't fully understand when these changes start or what causes them. This study will help fill that knowledge gap by measuring blood vessel stiffness, blood pressure, and special blood markers in children at different time points.
Heart and blood vessel damage has traditionally been thought of as a long-term complication of type 1 diabetes that only shows up in adults. However, recent research suggests these changes may start earlier than expected—even in children. There is also very little information about how this happens in Canadian children, which is why this study is important.
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You would visit the hospital five times over two years: at the time of your diabetes diagnosis, and then again at 6 months, 12 months, 18 months, and 24 months after diagnosis. At each visit, you'll have your blood vessels checked using ultrasound and other non-invasive devices, wear a blood pressure monitor for 24 hours, give a blood sample, and answer questions about your diet, activity level, and health. The whole process takes a few hours per visit and helps doctors understand how your heart and blood vessels are doing.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Canada
Sponsor
University of British Columbia
Collaborators
Canadian Institutes of Health Research (CIHR), BC Children's Hospital Research Institute
Enrollment target
~150 participants
Started
March 2024
Primary completion
September 2027
Age range
8 Years – 18 Years
Last updated on clinicaltrials.gov in May 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Angela Devlin, PhD
UBC Pediatrics/BC Children's Hospital Research Institute
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.