Plain-English translation of NCT05797649 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
When your heart isn't pumping well, fluid can build up around your lungs — a condition called pleural effusion. Doctors currently use several tests to figure out if heart failure is causing this fluid. This study is testing whether a new marker called NT-proBNP, measured in the fluid itself, can identify heart failure-related fluid buildup better than the tests doctors use today.
Right now, doctors have to use multiple tests and sometimes guesswork to figure out whether heart failure is causing fluid around your lungs. If this new marker works better, it could give doctors a clearer, faster answer — helping them treat you more quickly and accurately.
You likely qualify if…
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If you join, your doctor will perform a standard procedure to collect a small sample of fluid from around your lungs — something they may already be planning to do for your care. The research team will then test this fluid for the new marker along with standard measurements. Your doctors will follow up with you for 3 months afterward to confirm what caused your fluid buildup, but your regular care won't change.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Hong Kong
Sponsor
Chinese University of Hong Kong
Collaborators
Roche Diagnostics GmbH
Enrollment target
~120 participants
Started
July 2023
Primary completion
November 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in November 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Christopher Chan, MBChB
Chinese University of Hong Kong
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.