Plain-English translation of NCT05799664 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a treatment called Targeted Lung Denervation (TLD), which uses radiofrequency energy to reduce nerve signals in the lungs. Researchers believe that calming these overactive nerves may help people with COPD experience fewer symptoms and better breathing. Half of the participants will receive the actual procedure, while the other half will receive a sham procedure (a fake version) to fairly compare how well the treatment works.
COPD causes the airways to narrow and make breathing difficult, and current medications don't work well enough for everyone. This trial is testing whether this new treatment can give people relief when standard medicines aren't enough.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you'll visit a research clinic where doctors will perform either the actual lung nerve procedure or a sham procedure using general anesthesia and a bronchoscope (a thin camera passed through your airways). All participants will continue taking their regular COPD medications. You'll be asked to complete breathing tests, keep a symptom diary, and attend follow-up visits over 12 months so researchers can track how well the treatment works and watch for any side effects.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
China
Sponsor
Hangzhou Broncus Medical Co., Ltd.
Enrollment target
~200 participants
Started
July 2023
Primary completion
February 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
40 Years – 75 Years
Last updated on clinicaltrials.gov in January 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Liheng Xie
West China Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.