Plain-English translation of NCT05803382 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing a new cancer medication called ZEN003694 combined with , a standard chemotherapy drug. Researchers want to find the right dose of the medication that is safe and works well when given together with . They will also study how well this combination fights cancer and how your body processes these drugs.
Many patients with advanced cancers stop responding to standard chemotherapy alone. This trial is exploring whether adding this medication to standard treatment might help the chemotherapy work better and give patients more treatment options.
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You will take the medication by mouth once daily and twice daily in a 2-weeks-on, 1-week-off schedule, with each full cycle lasting 3 weeks. Throughout the trial, you'll have regular CT or MRI scans, blood tests, and possibly biopsies to monitor how the treatment is working and check for side effects. After treatment ends, you'll have follow-up visits for safety monitoring at 30 days and then every 3 months for up to a year.
AI-generated summary from trial data · Jul 11, 2026 · Not medical advice
United States