Plain-English translation of NCT05806021 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing three different doses of —a steroid medication that is injected directly into the knee—to see if smaller amounts work just as well as the standard dose for treating knee arthritis. Doctors have used this injection for years, but no one has proven which dose is truly the best. This study will help answer that question.
Knee arthritis causes serious pain and limits what people can do, especially as they get older. While this medication is known to help, doctors currently choose doses based on habit rather than solid evidence. This trial will help determine whether smaller, safer doses might work just as well as the standard dose.
You likely qualify if…
You likely don't qualify if…
You will receive one steroid injection into your knee—randomly assigned to be either a 5 mg, 10 mg, or 40 mg dose. Neither you nor the doctor will know which dose you're getting until the study is complete. You will then be monitored over time with follow-up visits and questionnaires to track how much pain relief you get and how long it lasts, helping researchers understand which dose works best.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Canada