Plain-English translation of NCT05812963 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After a heart attack, patients with blockages in multiple coronary arteries (the vessels that supply blood to the heart) need treatment. Doctors must decide which arteries to open up. This trial compares two imaging methods—intravascular ultrasound (IVUS) and fractional flow reserve (FFR)—to see which one helps doctors make better treatment decisions and leads to better long-term health outcomes for patients.
Currently, doctors use visual inspection of heart images to decide which arteries need treatment, but this method has limitations. The trial is testing whether using one of two advanced imaging technologies—which provide either detailed pictures of artery walls or measurements of blood flow problems—leads to better decisions about which arteries actually need treatment stents.
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You will be randomly assigned to one of two groups. One group will receive an intravascular ultrasound (IVUS) scan to visualize the artery wall and guide treatment decisions. The other group will receive a fractional flow reserve (FFR) test using a special pressure wire to measure blood flow and guide decisions. Both are performed during the cardiac catheterization procedure. Your doctors will then treat your arteries based on which imaging method your group uses, and you will be followed over time to see how well you recover.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
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