Plain-English translation of NCT05819892 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing a new way to treat advanced endometrial cancer (stage IIIC) that has spread to lymph nodes. After surgery to remove the cancer, you would receive a combination of radiation therapy, chemotherapy, and a drug called (an immunotherapy that helps your immune system fight cancer). The study wants to see if this combination is safe and whether it can help prevent the cancer from coming back.
Standard treatments for this advanced type of endometrial cancer don't work well enough for many patients. Researchers believe that adding immunotherapy to the usual radiation and chemotherapy may help more patients survive longer and stay cancer-free.
You likely qualify if…
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You would receive treatment in phases: first, radiation combined with chemotherapy and the new medication for about 6 weeks, then additional chemotherapy cycles, and finally the immunotherapy medication alone for up to 2 years. Throughout treatment, you'll have regular clinic visits and blood tests to monitor your health and watch for side effects. After active treatment ends, you'll have follow-up visits every 6 months for 5 years to check how you're doing.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
United States