Plain-English translation of NCT05830591 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand whether children with autism have differences in the bacteria that live in their gut and mouth compared to children without autism. Scientists know that gut bacteria play an important role in digestion, immune health, and even brain function. This study will collect samples from children with autism and compare them to healthy children to see if there are meaningful differences.
Children with autism often experience stomach and digestive problems, and some recent research suggests that the bacteria living in the gut and mouth may play a role in autism symptoms. This trial exists to explore that possible connection and could help doctors better understand and support children with autism in the future.
If your child is enrolled, you will visit the hospital or clinic for a routine appointment. Researchers will collect small samples — likely stool and saliva samples from your child's mouth — to study the bacteria present. For younger children (ages 1–5), this happens during an initial evaluation; for older children (ages 6–17), samples may be collected during a regular dental cleaning visit. The study involves no medication or invasive procedures, just sample collection.
AI-generated summary from trial data · Jun 8, 2026 · Not medical advice
Italy
Enrollment target
~86 participants
Started
May 2021
Primary completion
December 2024
Age range
1 Year – 17 Years
Last updated on clinicaltrials.gov in June 2024.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Manola Comar, BSc
Institute for Maternal and Child Health IRCCS Burlo Garofolo