Plain-English translation of NCT05833659 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing two different approaches to breast reconstruction surgery in women with early-stage breast cancer who need a mastectomy (complete breast removal) while preserving the nipple. One approach places the implant in front of the chest muscle (prepectoral), and the other places it behind the chest muscle (subpectoral). The study will compare how satisfied women are with their results using both methods.
Doctors want to understand which breast reconstruction method gives women better cosmetic results and greater satisfaction after nipple-sparing mastectomy. This information will help future patients and surgeons make the best choice for their individual situation.
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You would undergo a minimally invasive nipple-preserving mastectomy using an endoscopic technique, followed by breast reconstruction with an implant. You would be randomly assigned to receive reconstruction using one of the two surgical approaches (implant placed in front of or behind your chest muscle). After surgery, you would be followed up to assess your satisfaction with your breast appearance and surgical outcomes.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
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