Plain-English translation of NCT05840575 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study, called MyBrain, investigates cognitive impairment—problems with memory, attention, and thinking—that can occur in young cancer patients during and after treatment. Researchers will use neuropsychological tests, brain imaging called EEG, blood tests for biomarkers, and quality-of-life surveys to understand when and how these thinking changes happen, and whether they improve over time.
Many young cancer patients report difficulties with concentration, learning, and mental fatigue that can last years after treatment ends. However, doctors don't yet know exactly when these thinking problems start, how long they last, or which brain functions are most affected in children and young adults. This study aims to fill that gap so treatments can be improved in the future.
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You will visit the hospital at several time points—before, during, and after your cancer treatment—for cognitive testing, brain scans (EEG), blood draws, and questionnaires about fatigue and quality of life. A healthy peer matched to you (by age and social circle) will also participate as a comparison. The study follows you over months or even years depending on your treatment length, helping researchers see how your thinking and brain function change over time.
AI-generated summary from trial data · Jul 6, 2026 · Not medical advice
Denmark
Sponsor
Rigshospitalet, Denmark
Enrollment target
~100 participants
Started
March 2022
Primary completion
March 2027
Age range
7 Years – 29 Years
Last updated on clinicaltrials.gov in May 2023.
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Central contact
Lisa L Hjalgrim, PhD, MD
Rigshospitalet, Denmark
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