Plain-English translation of NCT05841199 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Ventricular tachycardia is a dangerous rapid heart rhythm that some people handle well without symptoms, while others become dangerously unstable. This study tests whether measuring blood pressure and blood flow in the heart arteries during simulated rapid heart rhythms can predict who will tolerate this condition safely. By understanding these differences, doctors may be able to help patients avoid unnecessary implantable defibrillators or better predict who truly needs one.
Right now, doctors often recommend an implantable defibrillator (a device that shocks the heart if dangerous rhythms occur) for everyone with this condition, but the shocks can be harmful and distressing, and many are unnecessary. If researchers can identify which heart factors make someone stable or unstable during rapid rhythms, doctors could treat people more precisely or help patients make better informed decisions about whether they really need a defibrillator.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will be part of a study group based on your heart condition (such as normal heart function, coronary artery disease, or heart failure). During your scheduled coronary angiogram, the doctor will pace your heart at several faster rates while measuring your blood pressure and the blood flow in your coronary arteries. If you need a stent placed during the procedure, the measurements will be repeated afterward to see if blood flow improves. The study takes place during a single procedure visit, with no extra hospital stays required.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
United Kingdom
Sponsor
Imperial College London
Enrollment target
~70 participants
Started
August 2023
Primary completion
June 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2026.
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Central contact
Rahul Bahl
Senior Clinical Research Fellow
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