Plain-English translation of NCT05845021 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new care pathway for people with osteoporosis (weak bones) who need hip or knee replacement surgery. Instead of the usual approach, some participants will be referred to a bone health specialist (endocrinologist) before surgery for a virtual visit to review their bone health, start appropriate medications, and learn more about managing their condition. The study wants to see if this extra step helps prevent surgical complications.
People with osteoporosis who have hip or knee surgery face a higher risk of complications from their implants. This trial exists to find out whether connecting patients with a bone health specialist before surgery—rather than waiting until after—can prevent these problems and improve outcomes.
You likely qualify if…
You likely don't qualify if…
If you are randomly chosen for the bone health specialist pathway, your surgeon will refer you to see an endocrinologist (bone health doctor) for a virtual consultation before your surgery. You will have some extra blood tests done to check your bone health, and the specialist will review your bone density scan, start you on medications if needed, and teach you about managing weak bones. If you are in the standard care group, your surgeon will tell you that you have osteoporosis and ask you to follow up with your primary care doctor about it.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Sponsor
Johns Hopkins University
Enrollment target
~2,000 participants
Started
September 2023
Primary completion
October 2027
Age range
50 Years and older
Last updated on clinicaltrials.gov in October 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Savyasachi C Thakkar, MD
Johns Hopkins School of Medicine
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.