Plain-English translation of NCT05849012 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is a pilot study examining whether a low sulfur diet can help reduce ongoing symptoms like abdominal pain and diarrhea in people with Crohn's disease that is not currently active. The study is based on the idea that the bacteria living in your gut may contribute to these persistent symptoms, and diet can influence those bacteria. Over 8 weeks, half of participants will follow a low sulfur diet while the other half continue their usual eating habits.
Even when Crohn's disease is well-controlled, nearly half of patients still experience bothersome symptoms like pain and diarrhea that hurt their quality of life. Currently, there are no proven treatments for this problem because doctors don't fully understand what causes it. This study explores whether changing diet could be a simple way to help.
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You'll start with a phone call to check if you're a good fit and review your current diet with a nutritionist. Then you'll have an in-person baseline visit where you'll undergo several tests (including stool, saliva, and urine samples) and be randomly assigned to either the low sulfur diet group or the usual diet group. Over the next 8 weeks, you'll have phone check-ins every 2 weeks with the study team, and finish with a final in-person visit for repeat testing. The low sulfur diet focuses on fruits, vegetables, whole grains, nuts, seeds, and soy products while limiting meat, dairy, eggs, and certain food additives.
AI-generated summary from trial data · Jun 20, 2026 · Not medical advice
United States