Plain-English translation of NCT05851443 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether a new medication called can help people whose asthma isn't well controlled even though they're already on strong daily inhalers. Researchers want to find the best dose of the medication by comparing it to a placebo (a dummy pill with no medicine) in about 247 participants. The trial will last about one year total, with 24 weeks of testing followed by 28 weeks of an extension period.
Many people with moderate to severe asthma continue to have symptoms and asthma attacks even when taking standard medications. This trial is testing whether this medication could offer better control and reduce the number of asthma attacks for people whose current treatment isn't working well enough.
You would take a daily pill once a day for the entire study period. For the first 24 weeks, you would either get the new medication at one of three different doses or a placebo, while continuing your regular asthma inhalers. After that, you would continue for another 28 weeks. Throughout the study, you would visit the clinic regularly so doctors can check your lung function, ask about your symptoms and asthma attacks, and make sure the treatment is safe.
AI-generated summary from trial data · Jul 13, 2026 · Not medical advice
United States