Plain-English translation of NCT05857969 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing a personalized approach to treating children with cancer that has returned or stopped responding to standard chemotherapy. Researchers will take a small sample of your child's tumor tissue and test it in the lab to see which medications work best against it, then use genetic testing to understand the tumor better. This information helps doctors choose the treatment most likely to help your child.
When childhood cancers come back or stop responding to standard treatments, doctors often struggle to know which medication to try next. This study exists to see whether testing the tumor directly can guide better treatment choices and improve outcomes for children facing these difficult situations.
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Your child's tumor sample (which may already be collected during a routine biopsy or surgery) will be sent to the research lab where scientists will test it against different medications to see which ones work best, and analyze the tumor's genetics. Your child will also have a blood draw or cheek swab for additional genetic testing. The research team will share these results with your child's doctor to help guide treatment decisions going forward.
AI-generated summary from trial data · Aug 31, 2026 · Not medical advice
United States