Plain-English translation of NCT05857969 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing a new approach called Functional Precision Medicine, which combines two tools: laboratory testing of how a patient's own tumor responds to different drugs, and genetic analysis of the tumor. The goal is to help doctors choose the most effective treatment for each child's specific cancer, rather than using a one-size-fits-all approach.
Many children with cancer have tumors that come back or don't respond to standard treatments. This trial exists to see if personalizing treatment based on how an individual patient's tumor behaves in the lab could help find better options for these children.
You likely qualify if…
You likely don't qualify if…
If you qualify, doctors will use tumor tissue from your biopsy or surgery (which you may already be having) to run laboratory tests on how your cancer responds to different drugs, and to analyze your tumor's genes. Your doctor will use these results to help decide which treatment might work best for you. You will also provide a blood sample or cheek swab for genetic testing. The study will then track how well the personalized treatment works for you compared to standard treatment approaches.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States