Plain-English translation of NCT05858008 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is a small pilot study testing whether time-restricted eating (eating all your daily calories within a set 10-hour window) might help women with mild cognitive impairment—early memory and thinking problems. Researchers will measure whether this eating pattern affects your metabolism, sleep, activity levels, and cognitive function over 8 weeks.
Scientists are exploring whether changing the timing of when we eat—rather than just what we eat—might support brain health and slow cognitive decline. This study will show whether this approach is practical and safe for women with early memory loss.
You likely qualify if…
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You'll come in for baseline testing during the first two weeks, where researchers will collect blood work, measure your body, check your sleep and activity patterns, and do cognitive testing. Then you'll spend 8 weeks eating all your daily calories within a 10-hour window that you choose yourself—texting researchers when you eat your first and last meal each day. Finally, you'll return for follow-up testing to measure any changes in your metabolism, sleep, activity, and cognitive function.
AI-generated summary from trial data · Jul 15, 2026 · Not medical advice
United States
Sponsor
Julie Pendergast
Collaborators
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Enrollment target
~15 participants
Started
April 2024
Primary completion
June 2027
Age range
45 Years – 95 Years
Sex
Female only
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Matt Thomas, PhD
University of Kentucky
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.