Plain-English translation of NCT05865327 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a procedure called cryoneurolysis, which uses a handheld device to gently freeze the nerves that carry pain signals from broken ribs. The goal is to see whether this treatment, added to standard pain-relief approaches, can provide longer-lasting pain control than current methods alone. The procedure is guided by ultrasound to make sure it's done safely and accurately.
Over 100,000 people a year suffer broken ribs from accidents, and the pain can be severe and long-lasting, making it hard to breathe deeply or cough—which can lead to serious complications. Current pain treatments work, but their effects don't last very long. This trial is exploring whether freezing the nerves could offer pain relief that lasts much longer, helping people recover faster and improve their quality of life.
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You will be randomly assigned to receive either the nerve-freezing procedure plus standard pain management, or standard pain management alone (with a sham procedure to keep you blinded to which group you're in). All participants receive standard care including pain medications and a nerve catheter. The study takes place at a single hospital site, and you'll be followed with pain assessments and medication tracking. You'll need to return for a follow-up visit at 3 months to assess how well the treatment worked.
AI-generated summary from trial data · Sep 11, 2026 · Not medical advice
Canada