Plain-English translation of NCT05865600 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing the best timing for a heart procedure called cardiac catheterization in people with chronic chest pain caused by heart disease. All participants will first receive a special heart imaging scan called [15O]H2O cardiac PET/CT that measures blood flow to the heart. Then, some participants will be referred for the catheterization procedure right away, while others will wait three months while taking heart medications—helping doctors learn which approach works best.
Current guidelines recommend the catheterization procedure for people with large areas of reduced blood flow to the heart, but recent research suggests that waiting and optimizing medications first might work just as well. This trial will help determine whether the timing of the procedure affects how well people do.
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All participants will complete the special heart imaging scan (PET/CT) and answer questions about their symptoms. If you are chosen for the randomized part of the trial, you will be assigned to either receive a heart catheterization procedure right away or to wait three months while taking medications to manage your heart condition. You will have follow-up visits at three months and beyond, with your health tracked through national registries.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
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