Testing blood clot medications in patients with liver cirrhosis

This trial is testing how two blood clot prevention medications — apixaban and edoxaban — work in patients with mild to moderate liver cirrhosis. Researchers want to understand how the body processes these medications and whether they help prevent dangerous blood clots in people with liver disease, who are at higher risk for this serious complication.

Patients with liver cirrhosis have a much higher risk of developing blood clots, which can lead to serious complications. Doctors are often hesitant to prescribe blood clot prevention medications to these patients because they worry about side effects, but there is strong evidence that this treatment could actually help. This study aims to close the knowledge gap about whether these newer oral medications are safe and effective for people with liver cirrhosis.