Plain-English translation of NCT05871099 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing hyperthermic intraperitoneal chemotherapy (HIPEC) — a treatment that bathes the abdomen with heated chemotherapy during stomach cancer surgery — to see if it helps prevent cancer from coming back. Researchers want to know if adding this heated chemotherapy treatment to standard surgery and chemotherapy improves survival rates and reduces the chance that cancer spreads inside the abdomen.
Advanced stomach cancer often spreads to the lining of the abdomen, and this is a major reason patients don't survive long-term. Doctors are testing whether the heated chemotherapy treatment, applied directly to the abdomen during surgery, can kill cancer cells better than surgery and standard chemotherapy alone.
You likely qualify if…
You likely don't qualify if…
If you enroll, you will have laparoscopic (minimally invasive) stomach surgery with removal of surrounding lymph nodes. Half of participants will also receive the heated chemotherapy treatment twice during surgery; all participants will then receive standard chemotherapy through infusions over 6 to 8 cycles. You will be followed for at least 5 years to track your survival and whether cancer returns, with regular check-ups and imaging tests.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
China