Plain-English translation of NCT05871372 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Depression research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers at Baylor College of Medicine are studying how different areas of the brain affect mood and depression. They will use information gathered from brain monitoring devices already in place (for epilepsy or depression treatment) to understand the relationship between brain activity and your emotional state. The goal is to learn how to better treat depression through targeted brain stimulation in the future.
Current depression treatments don't work for everyone, and doctors need a better understanding of how brain stimulation can help. This study aims to map which brain regions control mood and how electrical stimulation changes brain activity, so researchers can develop more effective and personalized treatments.
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If you join this study, researchers will use brain recordings from electrodes already placed in your brain (for your epilepsy or depression treatment) to measure your brain activity while you report your mood and complete thinking tasks. You'll be asked to perform cognitive tests designed to measure aspects like reward sensitivity and problem-solving. Researchers will also test how your brain responds to gentle electrical stimulation and collect data on how stimulation affects your mood and brain activity over time.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States