Plain-English translation of NCT05873699 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This pilot study is testing whether a special MRI scan using hyperpolarized 13C-pyruvate can help doctors identify which pancreatic cysts are dangerous and which are safe. The scan measures how actively cancer cells are working in a cyst. Researchers will compare the scan results to what doctors find during surgery and in tissue samples to see if this imaging method could help guide future treatment decisions.
Pancreatic cysts are common, but doctors often cannot tell which ones are dangerous without surgery. This study aims to develop a safer, non-invasive imaging tool that could help identify truly dangerous cysts before surgery, potentially avoiding unnecessary operations.
You likely qualify if…
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Within four weeks before your scheduled surgery, you will come in for a special MRI scan lasting a couple of minutes, though you should expect to be at the facility for up to 30 minutes for preparation. During the scan, a medication called hyperpolarized 13C-pyruvate will be injected into your vein while doctors monitor your vital signs. The entire visit, including possible blood work, may take up to half a workday. After your surgery, researchers will compare what the scan showed to what the surgeon and pathologist found in your tissue.
AI-generated summary from trial data · Jul 19, 2026 · Not medical advice
United States
Phase
Safety & dosing
Sponsor
M.D. Anderson Cancer Center
Enrollment target
~20 participants
Started
August 2023
Primary completion
January 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in July 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Florencia McAllister, MD
M.D. Anderson Cancer Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.