Plain-English translation of NCT05875155 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study helps girls and women preserve their ability to have biological children in the future by freezing ovarian tissue before they receive cancer treatment or other therapies that may cause infertility. The researchers will safely remove and freeze a small amount of ovarian tissue before your treatment begins, then store it long-term so it may be used later when new fertility restoration technologies become available. This approach gives patients options they don't currently have, especially young girls who aren't yet able to freeze eggs or embryos.
Cancer treatments like chemotherapy and radiation can permanently damage or destroy a woman's eggs and fertility. Currently, adult women can freeze embryos or eggs, but this isn't an option for girls before puberty or women who can't delay treatment. This trial is developing ways to preserve ovarian tissue now so that future medical advances can help these patients have biological children later.
You likely qualify if…
You likely don't qualify if…
You would have a minor surgical procedure to remove and freeze a portion of ovarian tissue before your cancer treatment or other therapy begins. The frozen tissue will be stored long-term by the research team at the University of Pittsburgh. In the future, if and when new technologies are developed to restore fertility using frozen ovarian tissue, you may be able to use your preserved tissue to have biological children.
AI-generated summary from trial data · Jul 3, 2026 · Not medical advice
United States
Sponsor
University of Pittsburgh
Enrollment target
~500 participants
Started
January 2011
Primary completion
January 2031
Sex
Female only
Last updated on clinicaltrials.gov in March 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Rachel Neelley, BA
University of Pittsburgh/ University of Pittsburgh Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.