Lifestyle Changes to Prevent Memory Loss in Older Adults

This trial is testing whether a structured lifestyle program can slow down or prevent memory loss and dementia in older adults who are starting to show signs of cognitive decline. The program combines four key components: nutritional guidance, physical exercise, cognitive training (brain exercises), and close monitoring of heart and metabolic health. Researchers want to understand how these lifestyle changes affect the brain and whether they can protect memory and thinking skills as people age.

Memory loss and dementia affect millions of older adults, but most research on prevention has been done in Western countries, not Asia. This study exists to see whether a combined lifestyle approach—focusing on diet, exercise, brain health, and heart health—can actually prevent or delay cognitive decline in older Asian adults who are at high risk, and to understand the brain changes that make this happen.