Plain-English translation of NCT05888688 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →This study is looking at why some heart failure patients develop muscle weakness and fatigue. Researchers want to understand the differences in muscle strength, size, and quality between people with different types of heart failure, and they'll do this by having participants complete physical tests, walk tests, balance tests, and imaging scans of the leg muscles.
Heart failure can affect muscles throughout the body, leaving patients feeling weak and tired. By studying how muscles change in different types of heart failure, doctors hope to better understand and eventually treat the muscle weakness that makes daily life harder for these patients.
You likely qualify if…
You likely don't qualify if…
If you join this study, you'll visit the research center for assessments that include simple physical tests (like calf and thigh strength tests), a 6-minute walking test, and balance and standing tests. You'll also have an MRI scan of your leg muscles to look at muscle quality, and you may have a small muscle biopsy (a tiny sample of muscle tissue) taken. The study takes about one visit, though the exact duration depends on which group you're in, and researchers will gather information about your heart failure history and current health.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
United Kingdom